Association of chlorhexidine and high fluoride dentifrice on Streptococcus mutans viability using an in vitro biofilm model

Authors

  • Guilherme Bandeira Santana Dentistry Course of Federal University of Piauí
  • Debora Lima Silva Dentistry Course of Federal University of Piauí
  • Josie Haydée Lima Ferreira Microbiology and Parasitology Department, Federal University of Piauí
  • Fabiana Gouveia Rolim Postgraduate Program in Dentistry, Federal University of Piauí
  • Glauber Campos Vale Restorative Dentistry Department, Federal University of Piauí

DOI:

https://doi.org/10.14295/bds.2016.v19i3.1258

Abstract

Objective. This in vitro study investigated the effect of Fluoride (F), Chlorhexidine (CHX), and their association on the viability of Streptococcus mutans using a biofilm model. Materials and Methods. Biofilms were anaerobically grown on glass slides that were vertically suspended in 24-well plates for 5 days.  After 48 h of initial growth, biofilms were treated for the next 72 h, 2x/day with CHX at 0.12% and 2%, F as NaF at 0.08% and 0.4% and their association. Results. CHX treatment decreased the bacteria counts either alone or in association with both F concentrations, when compared with control group and the F treatments alone (p<0.05). Conclusion. No addition effect was observed when CHX and F were used in combination, when compared with CHX used alone.     

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Published

2016-09-29

How to Cite

1.
Santana GB, Silva DL, Ferreira JHL, Rolim FG, Vale GC. Association of chlorhexidine and high fluoride dentifrice on Streptococcus mutans viability using an in vitro biofilm model. BDS [Internet]. 2016 Sep. 29 [cited 2025 Aug. 21];19(3):9-13. Available from: https://ojs.ict.unesp.br/index.php/cob/article/view/1258

Issue

Vol. 19 No. 3 (2016): Jul. - Sep. / 2016 - Published September 2016

Section

Short Communication

License

Brazilian Dental Science uses the Creative Commons (CC-BY 4.0) license, thus preserving the integrity of articles in an open access environment. The journal allows the author to retain publishing rights without restrictions.

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