Evaluating Cytotoxic Effects of Highly Esthetic Dental Composites
DOI:
https://doi.org/10.14295/bds.2020.v23i1.1883Abstract
Amaç: Di? hekimli?i alan?nda nanoteknoloji alan?nda odakl? di? kompozitler, ön ve arka di?lerin oldu?u yerlerde yayg?n olarak yap?l?r. L929 fare fibroblast sitotoksik oldu?u için in vitro ekstrakt test yöntemi ile ara?t?r?ld?.
Gereç ve Yöntemler: Steril bir dolapta cam moddaki led ???k cihaz?yla polimerle?tirilerek 8x2 mm çap?nda kompozit numuneler haz?rland?. Kompozit numuneler yüzey plakalar? (3 cm ISO standartlar?na göre 2 / ml hesapland? ), 37 ° C s?cakl?kta, 24 ve 72 saat süre ile inkübe edildi O C. Hücre canl?l???, 3- [4,5-dimetiltiyazol-2-il ile de?erlendirildi] -2,5-difeniltetrazolyum bromür (MTT) deneyi ve hücre ölümü laktat dehidrojenaz (LDH) s?z?nt? deneyi ile de?erlendirildi.
Sonuçlar: 24 saatin sonunda kompozitlerin 1: 1 ekstraktlar? (nanoseramik kompozit hariç) toksik etki göstermedi. Kompozit numunelerin 1: 1 ekstrelerinin hücre canl?l??? sonuçlar?, 72 saat sonra analiz edilece?i halde, kontrol grubuna göre anlaml? farkl?l?klar bulundu (p <0.05).
Sonuç: Dolgu tipinin ve boyutunun kompozitlerin toksisitesinde etkili olmas? ve organik matrikslerde Bis-GMA, TEGDMA, UDMA ve Bis EMA monomerlerini içeren kompozitlerin istenildi?i yerde canl? canl?l??? (% 70) gösterdi?i görülmektedir. ISO taraf?ndan söyildi. Orada birlikte, organik matrislerinde PEGDMA ve BPA monomerlerine sahip olan, sahip olan kompozitler,% 70'in oldu?u kabul edilebilir seviyesinin alt?nda olan ve toksik olan bir ve Türkiye'nin sahip ve zay?f ortamdaki canl?l??? vard?r.
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