Avaliação imuno-histoquímica do antígeno nuclear de proliferação celular (pcna) e da proteína p 53 em ameloblastoma tratados pela técnica da marsupialização I
DOI:
https://doi.org/10.14295/bds.2006.v9i1.265Abstract
OBJETIVO: O propósito deste estudo foi avaliar a proliferação celular de ameloblastomas antes e depois de submetidos à técnica cirúrgica da marsupialização.MÉTODOS: quatro casos de ameloblastomas submetidos à marsupialização foram examinados imuno-histoquimicamente para a expressão do antígeno nuclear de proliferação celular (PCNA) e da proteína p53, em dois momentos do tratamento: na cirurgia inicial de descompressão e na subseqüente enucleação. RESULTADOS: Observamos que a reatividade imuno-histoquímica para o PCNA e proteína p53, após a marsupialização, diminuiu em dois casos e aumentou em dois dos espécimes estudados. CONCLUSÃO: A marsupialização em ameloblastomas nem sempre é capaz de causar redução na atividade proliferativa das células tumorais.Downloads
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