Cemento-ossifying fibroma with aneurysmal bone cyst-like cystic hemorrhagic degeneration in the mandible: a case report and literature review

Authors

  • Dhara Schrok Monteiro de Ataide Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Cirurgia, Estomatologia, Patologia e Radiologia, Área de Patologia, Bauru, SP, Brazil. https://orcid.org/0009-0001-0349-9463
  • Kaique Alberto Preto Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Cirurgia, Estomatologia, Patologia e Radiologia, Área de Patologia, Bauru, SP, Brazil. https://orcid.org/0000-0001-6991-209X
  • Gabriela Lopes dos Santos Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Cirurgia, Estomatologia, Patologia e Radiologia, Área de Patologia, Bauru, SP, Brazil. https://orcid.org/0000-0001-9976-9511
  • Marcelo Júnior Zanda Universidade de São Paulo, Centro de Pesquisa Clínica, Faculdade de Odontologia de Bauru, Bauru, SP, Brazil. https://orcid.org/0000-0001-7519-5285
  • Denise Tostes Oliveira Universidade de São Paulo, Faculdade de Odontologia de Bauru, Departamento de Cirurgia, Estomatologia, Patologia e Radiologia, Área de Patologia, Bauru, SP, Brazil. https://orcid.org/0000-0002-4628-7129

DOI:

https://doi.org/10.4322/bds.2025.e4680

Abstract

Although rare, the aneurysmal bone cyst remains the most frequently associated lesion with cemento-ossifying fibroma in jawbones, with a higher prevalence in young people in their second decade of life. Nowadays, the concept of a secondary aneurysmal bone cyst has been replaced by that of cystic hemorrhagic degeneration, producing an aneurysmal bone cyst-like appearance in the fibro-osseous lesion. Objective: This study aims to report an uncommon case of cemento-ossifying fibroma associated with aneurysmal bone cyst-like cystic hemorrhagic degeneration in the mandible of a middle-aged woman and to review its clinical, imaging and histopathological features. Case report: A 44-year-old Caucasian woman was referred for evaluation of a painless, slow-growing swelling in the region of teeth 33, 34, and 35, which presented normal pulpal vitality. Cone-beam computed tomography revealed a periapical hypodense area with hyperdense foci involving the roots of the affected teeth, associated with the expansion and rupture of the buccal cortical bone. The diagnosis established was cementoossifying fibroma with aneurysmal bone cyst-like cystic hemorrhagic degeneration. Conclusion: The cementoossifying fibroma associated with aneurysmal bone cyst-like cystic hemorrhagic degeneration, as described in this case, is uncommon in the jawbones. The correlation of clinical, imaging, and microscopic features is crucial for an accurate diagnosis.

KEYWORDS

Aneurysmal bone cyst; Cemento-ossifying fibroma; Fibro-osseous lesion; Odontogenic tumor; Ossifying fibroma.

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Published

2025-08-12

How to Cite

1.
Ataide DSM de, Preto KA, Santos GL dos, Zanda MJ, Oliveira DT. Cemento-ossifying fibroma with aneurysmal bone cyst-like cystic hemorrhagic degeneration in the mandible: a case report and literature review. BDS [Internet]. 2025 Aug. 12 [cited 2025 Aug. 21];28(2). Available from: https://ojs.ict.unesp.br/index.php/cob/article/view/4680

Issue

Section

Case Report or Clinical Technique