Expressão do gene p53 no carcinoma bucal: revista da literatura. Influência da esterilização em estufa sobre cones de papel absorvente para endodontia
DOI:
https://doi.org/10.14295/bds.1999.v2i2.51Abstract
A busca por marcadores biológicos que auxiliem no diagnóstico, prognóstico e tratamento das neoplasias é intensa. O diagnóstico precoce é importantíssimo para a sobrevida do paciente e o p53 tem sido amplamente estudado. O gene p53 está localizado no cromossomo 17p13.1 e sua mutação é a alteração mais comum nas neoplasias humanas. A maioria das mutações ocorre em células somáticas, porém formas herdadas também foram encontradas. Neste artigo é feita uma breve revista sobre a carcinogênese bucal e a expressão de p53.
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