Osteoporosis and periodontitis: a bidirectional relationship

Autores/as

  • Paramjit Kaur Khinda Department of Periodontology – Genesis Institute of Dental sciences and Research – Punjab – India.

DOI:

https://doi.org/10.14295/bds.2017.v20i2.1247

Resumen

Osteoporosis is a condition of compromised bone strength that predisposes an individual to increased risk of fracture and is a major cause of morbidity in older susceptible individuals. Osteoporosis is related to various endocrinal abnormalities, metabolic and nutritional factors, postmenopausal hormonal changes and consumption of certain drugs such as cortisone. Emerging clinical and molecular evidence suggests that inflammation also exerts significant influence on osteoporotic bone changes. Numerous pro-inflammatory cytokines have been shown to be associated with regulation of osteoblast and osteoclast differentiation. Chronic inflammatory conditions causing immune system remodeling may serve as pathological risk factors for osteoporosis. The present article reviews the current perspective on the interaction between bone morphology and immune system in the inflammatory condition (periodontitis), unleashing the link between two chronic conditions.

Keywords

Osteoporosis; Periodontitis; Inflammation; Bone remodelling.

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Biografía del autor/a

Paramjit Kaur Khinda, Department of Periodontology – Genesis Institute of Dental sciences and Research – Punjab – India.

 

 

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Publicado

2017-06-28

Cómo citar

1.
Khinda PK. Osteoporosis and periodontitis: a bidirectional relationship. BDS [Internet]. 28 de junio de 2017 [citado 10 de septiembre de 2025];20(2):19-28. Disponible en: https://ojs.ict.unesp.br/index.php/cob/article/view/1247

Número

Vol. 20 Núm. 2 (2017): Apr. - Jun. / 2017 - Published Jun 2017

Sección

Literature Review

Licencia

Brazilian Dental Science uses the Creative Commons (CC-BY 4.0) license, thus preserving the integrity of articles in an open access environment. The journal allows the author to retain publishing rights without restrictions.

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