Comparative evaluation of inter appointment pain and analgesic intake with calcium hydroxide and triple antibiotic paste as intracanal medicaments in patients with apical periodontitis – a randomized controlled single-blinded clinical trial

Interappointment and analgesic intake on using two different medicaments

Authors

  • Sanu Narayanan Saveetha University, Saveetha Institute of Medical & Technical Sciences, Saveetha Dental College & Hospitals, Department of Conservative Dentistry & Endodontics. Chennai, Tamil Nadu, India. https://orcid.org/0000-0001-7132-3884
  • Kavalipurapu Venkata Teja Saveetha University, Saveetha Institute of Medical & Technical Sciences, Saveetha Dental College & Hospitals, Department of Conservative Dentistry & Endodontics. Chennai, Tamil Nadu, India. https://orcid.org/0000-0003-0123-8873
  • Sindhu Ramesh Saveetha University, Saveetha Institute of Medical & Technical Sciences, Saveetha Dental College & Hospitals, Department of Conservative Dentistry & Endodontics. Chennai, Tamil Nadu, India. https://orcid.org/0000-0003-2617-6592

DOI:

https://doi.org/10.4322/bds.2022.e2536

Abstract

Objective: This study aimed to evaluate the effect of calcium hydroxide and triple antibiotic paste as intracanal
medication on the interappointment pain at 8, 24, and 48 hours postoperatively in patients with symptomatic
apical periodontitis undergoing multiple visit root canal treatment. Material and Methods: Two hundred and
seven systemically healthy patients under the age group of 18-45 years with mandibular molars presenting with
symptomatic apical periodontitis which require root canal treatments were included in this study. After access
cavity preparation, cleaning and shaping was done till ISO 25 size file, and the patients were randomized into
three groups (each group of 69 samples). Group I: no medicament, group II: calcium hydroxide and group III:
triple antibiotic paste (TAP). Postoperative pain was evaluated at 8 hours, 24 hours and 48 hours. Results:
The results showed that at 8 hours, 24hours and 48hours, there was a statistical difference between I and III
(p < 0.05); and Group III and Group II (p < 0.05). Within the group, there was a statistical difference at all
time points IN Group I and II (p < 0.05) except between 24 hours and 48 hours in the Group III (p > 0.05).
Conclusion: Within the limitations of this study, TAP was more effective than calcium hydroxide in relieving
pain and reducing the analgesic intake at the first 24hours.
KEYWORDS
Intracanal medicament; Calcium hydroxide; Triple antibiotic paste; Interappointment pain; Apical periodontitis.

Author Biographies

Sanu Narayanan, Saveetha University, Saveetha Institute of Medical & Technical Sciences, Saveetha Dental College & Hospitals, Department of Conservative Dentistry & Endodontics. Chennai, Tamil Nadu, India.

Department of Conservative & Endodontics, Saveetha Dental College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Chennai, Tamil Nadu India

Kavalipurapu Venkata Teja, Saveetha University, Saveetha Institute of Medical & Technical Sciences, Saveetha Dental College & Hospitals, Department of Conservative Dentistry & Endodontics. Chennai, Tamil Nadu, India.

Department of Conservative & Endodontics, Saveetha Dental College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Chennai, Tamil Nadu India

Sindhu Ramesh, Saveetha University, Saveetha Institute of Medical & Technical Sciences, Saveetha Dental College & Hospitals, Department of Conservative Dentistry & Endodontics. Chennai, Tamil Nadu, India.

Department of Conservative & Endodontics, Saveetha Dental College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Chennai, Tamil Nadu India

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Published

2021-08-06 — Updated on 2022-06-23

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Clinical or Laboratorial Research