How can the dental surgeon promote oral health in patients submitted to chemotherapy?
DOI:
https://doi.org/10.4322/bds.2022.e3013Abstract
Lesions that affect the oral cavity resulting from chemotherapy can lead to systemic impairment, increasing the
length of hospital stay, impairing the patient’s quality of life. Through a integrative review, this work aims to
show the conduct and importance of dentists in promoting oral health and preventing an oral infectious focus.
The search was performed in the Pubmed, Cochrone, SciElo and Virtual Health Library (VHL) databases, using
the descriptors in English, oral care and Chemotherapy and Cancer treatment and dentistry, filtering only articles
in English and published between 2006 and 2021. The search located six hundred and twenty articles, but only
seven met the search criteria. One author used a mouthwash containing propolis where 65% of patients were
cured on the seventh day after the onset of oral mucositis (OM) lesions. One author used cryotherapy with
chamomile infusion, patients who underwent this approach did not pass grade I, being effective in reducing
the occurrence of OM, and the other two authors proposed a protocol for oral cavity care. All authors obtained
satisfactory results.
KEYWORDS
Dentistry; Antineoplastics; Oncology.
References
Lobão DS, Oliveira BM, Massara MLA, Viana MB, Nunes L. Conditions of the oral cavity and of dental attendance of children with acute lymphocytic leukemia.Rev Med Minas Gerais. 2008; 18, 25-32.
Patussi C, Sassi LM, Munhoz EC, ZaniCott RTS. Clinical assessment of oral mucositis and candidiasis compare to chemotherapic nadir in transplanted patients. Braz Oral Res. 2014; 28, 1-7. Doi: 10.1590 / 1807-3107BOR-2014.vol28.0050.
Glenny MA, Gibson F, Auld E, Coulson S, Clarkson JE, Craig JV. et al. The development of evidence-based guidelines on mouth care for children, teenagers and young adults treated for cancer. European journal of cancer. 2010; 46, 1 3 9 9 –1 4 1 2. DOI: 10.1016 / j.ejca.2010.01.02.
Hespanhol FL, Tinoco BEM, Teixeira HGC, Falabella MEV, Assis NMSP. Buccal manifestations in patients submitted to chemotherapy. Ciência & Saúde Coletiva. 2010; 15, 1085-1094.
Walsh LJ. Clinical assessment and management of the oral environment in the oncology patient. Australian Dental Journal. 2010; 55, 66-77.
Lalla, RV, Bowen J, Barasch A, Elting L, Epstein J, Keefe DM. MASCC=ISOO Clinical Practice Guidelines for the Management of Mucositis Secondary to Cancer Therapy. 2014; 1453-1461. DOI: 10.1002/cncr.28592.
Reis PLD, Ciol MA, Melo NS, Figueiredo PTS, Leite AF, Manzi NM. Chamomile infusion cryotherapy to prevent oral mucositis induced by chemotherapy: a pilot study.Cancer Care apoio. 2016; DOI 10,1007 / s00520-016-3279-y.
Akhavan-karbassi MH, Yazdi MF, Yazdi H, Sadr-Abad MJ. Randomized Double-Blind Placebo-Controlled Trial of Propolis for Oral Mucositis in Patients Receiving Chemotherapy for Head and Neck Cancer.Asian Pac J Cancer Prev. 2016; 17( 7), 3611-3614.
PACHEKENAR, A.K.P.F. et al. The effect of an oral care protocol and honey mouthwash on mucositis in acute myeloid leukemia patients undergoing chemotherapy: a single-blind clinical trial. Clinical Oral Investigations. 2018.
Saito H, Watanabe Y, Sato K, Ikawa H, Yoshida Y, Katakura A. et al. Effects of professional oral health care on reducing the risk of chemotherapy-induced oral mucositis. Cancer Care Support Japan. 2014; 22, 2935-2940.
DJURIC, M. et al. Mucositis prevention by improved dental care in acute leukemia patients. Support Care Cancer. v.14, p. 137–146, 2006.
Sonis ST. Mucositis as a biological process: a new hypothesis for the development of chemotherapy-induced stomatotoxicity. Oral Oncology. 1998; 34, 39-43.
Tsuji,K, Shibuya Y, Akashi M, Furudoi S, Yakushijin K, Kawamoto S. et al. Prospective Study of Dental Intervention for Hematopoietic Malignancy. Journal of Dental Research. 2015; 94, 289-296.
SAHNI, P. et al. Oral alterations and oral health-related quality of life assessment in patients undergoing chemotherapy at a tertiary care center. Spec Care Dentist. p.1–7, 2020.