Edemogenic test and hydrogen peroxide degradation rate of bleaching gels with different desensitizing agents

Authors

  • André Luiz Fraga Briso Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.
  • Marjorie Oliveira Gallinari Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.
  • Francine Benetti Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.
  • Diego Valentim Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.
  • Carlos Roberto Emerenciano Bueno Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.
  • Fabiano Carlos Marson Dental Press Ensino e Pesquisa Ltda – Maringa – PR – Brazil.
  • Eloi Dezan Junior Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.
  • Luciano Tavares Ângelo Cintra Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.

DOI:

https://doi.org/10.14295/bds.2018.v21i2.1526

Abstract

Objective: The at-home bleaching technique leads to the intimate contact of the bleaching gel with gingival tissues, so this study evaluated the immediate inflammatory response, through the edemogenic test, induced by at-home bleaching gels of 10% carbamide peroxide with different desensitizing agents, the quantification of hydrogen peroxide released and bleaching gels pH. Material and Methods: Forty-eight rats were divided into groups (n=12): CTRL-control group, WP-Whiteness Perfect 10% (FGM Produtos Odontológicos, Joinville, SC, Brazil), OPA-Opalescence 10% (Ultradent Products Inc., South Jordan, IT, USA), and PB-Power Bleaching (BM4, Palhoça, SC, Brazil). For the edemogenic test, all rats received an intravenous injection of Evan's Blue; after 30 min, 0.2 mL of each bleaching gels was injected into the subcutaneous tissue of the rats, and the results of the vascular permeability were assessed after 3 and 6h. The amount of HP released and pH of each product was also determined. Data were submitted to statistical test (p<0.05). Results: At 3h, the PB showed higher vascular permeability than the other groups. At 6h, the PB produced similar vascular permeability than WHI, and higher than OPA and CTRL groups. The OPA group had a higher vascular permeability at 6h compared to 3h; there is no difference in other groups. The PB group had higher HP concentrations than the other groups. Conclusion: In general, the PB caused a more considerable amount of inflammatory edema and higher amount of HP released. This results suggesting that these bleaching gels cause greater aggression in soft gingival tissues that eventually ends up in contact with bleaching products

 

Keywords

Tooth bleaching; Carbamide peroxide; Hydrogen peroxide; Capillary permeability.

Author Biographies

André Luiz Fraga Briso, Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.

Associate Professor, Department of Restorative Dentistry

Marjorie Oliveira Gallinari, Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.

DDS, MS, PhD student, Department of Restorative Dentistry

Francine Benetti, Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.

DDS, MS, PhD student, Department of Restorative Dentistry, 

Diego Valentim, Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.

DDS, MS, PhD student, Department of Restorative Dentistry

Carlos Roberto Emerenciano Bueno, Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.

DDS, MS, PhD student, Department of Restorative Dentistry,

Fabiano Carlos Marson, Dental Press Ensino e Pesquisa Ltda – Maringa – PR – Brazil.

DDS, MS, PhD, Associate Professor, Dental Press Ensino e Pesquisa Ltda, Maringa,

Eloi Dezan Junior, Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.

Associate Professor, Department of Restorative Dentistry

Luciano Tavares Ângelo Cintra, Department of Restorative Dentistry – Araçatuba Dental School – UNESP – Univ Estadual Paulista – Araçatuba – SP – Brazil.

Associate Professor, Department of Restorative Dentistry

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Published

2018-04-19

Issue

Vol. 21 No. 2 (2018): Apr. - Jun. / 2018 - Published April 2018

Section

Clinical or Laboratorial Research Manuscript